Effect of propofol versus sevoflurane on auditory and cognitive functions: a randomized controlled trial
نویسندگان
چکیده
Abstract Background Hearing loss and cognitive impairment are postoperative complications which need more awareness by anaesthesiologists. We set out to investigate whether sevoflurane or propofol would have a negative impact on auditory function, attention, memory. This is prospective randomized controlled study was conducted patients who were candidates for elective laparoscopic cholecystectomy under general anesthesia with either the propofol. All included participants subjected evaluation preoperative 1 week after operation. Cognitive assessment included: Paired Associate Learning test (PALT) Paced Auditory Serial Addition Test (PASAT). Audiological done measuring brainstem response (ABR). Results There no statistically significant difference between both groups in age ( p value = 0.537) sex 0.175). In group, values of LT ABR-I III significantly higher than ones < 0.001, 0.003), all RT ABR waves P 0.05). LTABR-I, III, III–V (0.012, 0.008 0.009) RTABR-III, V, I–III, 0.041, 0.029, 0.005 0.001). differences sides > worsening pre- PASAT scores groups, respectively, (< 0.001) 0.906). addition, there PALT group only 0.01) 0.038). Conclusions function attention following two drugs. Whereas, memory impaired only.
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ژورنال
عنوان ژورنال: The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
سال: 2023
ISSN: ['1687-8329', '1110-1083']
DOI: https://doi.org/10.1186/s41983-023-00680-0